Nattokinase Plus contains: Nattokinase 20,000FU/g (100mg), Vitamin E (as d-alpha tocopherol) 20 I.U. Nattokinase is a potent fibrinolytic enzyme extracted and highly purified from a traditional Japanese food called Natto. Blood clots (or thrombi) form when strands of protein called fibrin accumulate in a blood vessel. In the heart, blood clots cause blockage of blood flow to muscle tissue. If blood flow is blocked, the oxygen supply to that tissue is cut off and it eventually dies. This can result in angina and heart attacks. Clots in chambers of the heart can mobilize to the brain. In the brain, blood clots also block blood and oxygen from reaching necessary areas, which can result in senility and/or stroke. The human body produces several types of enzymes for making thrombus (blood clotting material), but only one main enzyme for breaking it down and dissolving it - plasmin. The properties of nattokinase closely resemble plasmin.
Researchers from JCR Pharmaceuticals, Oklahoma State University, and Miyazaki Medical College tested nattokinase on 12 healthy Japanese volunteers (6 men and 6 women, between the ages of 21 and 55). The tests indicated that the natto generated a heightened ability to dissolve blood clots. The Benefits of taking Nattokinase for High Blood Pressure The same natto extract was then tested on human volunteers with high blood pressure. Blood pressure levels were measured after 30 grams of lyophilized extract (equivalent to 200 grams of natto food) was administered orally for 4 consecutive days. In 4 out of 5 volunteers, the systolic blood pressure (SBP) decreased on average from 173.8 20.5 mmHg to 154.8 12.6 mmHg. Diastolic blood pressure (DBP) decreased on average from 101.0 11.4 mmHg to 91.2 6.6 mmHg. On average, this data represents a 10.9 percent drop in SBP and a 9.7 percent drop in DBP. Other ingredients: rice bran oil, gelatin, glycerin, purified water, lecithin, yellow beeswax, tumeric, and glycerin complex, titanium oxide. Warnings: Keep out of reach of children. Additional Info: Tamper evident band around cap and seal on bottle. Do not use if either seal is broken or missing. Packaging: White Plastic Other Ingredients: Rice Bran Oil, Gelatin, Glycerin, Purified Water, Lecithin (Soy), Yellow Beeswax, Turmeric and Glycerin Complex, Titanium Dioxide. Suggested Use: Two softgel capsules daily, or more, as directed by a doctor.